Life Tech

As always, Jonathan Rothberg did not disappoint and delivered some pretty bold statements about where they are heading with the Proton.

Some highlights:

• 500+ bp reads
• Better accuracy than Illumina
• Homopolymers not really an issue
• Genome for $1000 by end of 2012

Once again, we at EdgeBio are excited by the claims and are endeavoring to get our hands on a Proton as soon as they become available. Looking forward to generating data and sharing it with the community through this blog!

GNUbio Summary

Beta release mid 2012
Complete release end 2012

• Claim 40 seconds prep time and 3.5 hour run
• 2 instruments in R&D at this time
• Picoinjector droplet technology - exclusive license Injects gDNA into droplet containing PCR primer library
• Piece together 1kb reads -map sub assemblies to a reference Do local reconstruction

There are lots of pictures - not sure what they really mean....

City of Hope collaboration - Poster 338

• 1000bp read length claim
• Phred 70+ accuracy
• Yield/run 1.2 Gb
• Cost $200/sample

Dean