Sample Preparation PurElute™ IEX Plasmid Kits EdgeBio - Get the Edge. Edge BioSystems DNA Sequencing Reaction Cleanup Systems, DNA Purification and PCR Purification products.

PurElute™ IEX Plasmid Kits present a novel ion-exchange membrane for purification of superior quality endotoxin-free plasmid DNA. Membrane porosity was optimized to provide high interior surface area accessible for DNA binding and high flow rate for easy sample processing. This method is simpler and more efficient than conventional gravity flow columns. PurElute™ IEX Plasmid Kits have an exceedingly high binding capacity, excellent selectivity and recovery efficiency. Purified plasmid DNA is free of impurities that may interfere with demanding downstream applications.

See our article in the Journal of Biomolecular Techniques

Benefits

Superior quality DNA: Suitable for mammalian cell transfections and other sensitive downstream applications
High yield: Binding capacity greater than conventional gravity flow columns
Quick protocol: Significantly faster than conventional methods
Simple spin column format: No waiting for gravity flow columns
Broad applications: Purify plasmids of all sizes, cosmids, fosmids, and BACs
Ready to use: No pre-wetting or equilibration step
High purity DNA: Maxiprep provides endotoxin-free DNA
PurBlue: Visualize complete lysis to maximze DNA yield

Downstream Applications

Enzymatic modifications
Transfection of sensitive eukaryotic cells
Gene therapy research
In-vitro transcription/translation
Plasmid-mediated gene silencing